Do not use Actonel if:

• you are allergic to any ingredient in Actonel;
• you are unable to stand or sit upright for at least 30 minutes;
• you have low blood calcium levels or severe kidney problems.

• Actonel may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Actonel with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Talk to your doctor before you drink alcohol, smoke, or use other tobacco products while taking Actonel.
• Follow the diet and exercise program given to you by your health care provider. Talk to your doctor about whether you should take a calcium and vitamin D supplement while you use Actonel.
• Talk to your doctor about the use of weight-bearing exercises to help prevent weak bones.
• Proper dental care is important while you use Actonel. Brush and floss your teeth and visit the dentist regularly.
• Tell your doctor or dentist that you take Actonel before you receive any medical or dental care, emergency care, or surgery.
• Actonel may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Actonel.
• Lab tests, including bone density and blood calcium levels, may be performed while you use Actonel . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Actonel should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.
• Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Actonel while you are pregnant. It is not known if Actonel is found in breast milk. Do not breast-feed while taking Actonel.

Safety information

Check with your doctor if any of these most common side effects persist or become bothersome:

• back pain; constipation; diarrhea; dizziness; gas; headache; joint pain; mild stomach pain or upset; nausea.

• Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry or bloody stools; chest pain; coughing or vomiting blood; difficult or painful swallowing; mouth sores; new, worsening, or severe heartburn; painful or difficult urination; sensitivity to light; severe bone, muscle, or joint pain; severe or persistent sore throat or stomach pain; swelling of the arms or legs; swelling or pain in your jaw; unusual eye pain or redness; vision changes.

Actonel is to be used only by the patient for whom it is prescribed. Do not share it with other people.